IDENTIFICATION OF PATIENTS UNDERGOING CHRONIC KIDNEY REPLACEMENT THERAPY IN PRIMARY AND SECONDARY CARE DATA: VALIDATION STUDY BASED ON OPENSAFELY AND UK RENAL REGISTRY

Objective To validate primary and secondary care codes in electronic health records to identify people receiving chronic kidney replacement therapy based on gold standard registry data.Design Validation study using data from OpenSAFELY and the UK Renal Registry, with the approval of NHS England.Setting Primary and secondary care electronic health r

Abstract Background The evolutionary importance of horizontal gene transfer (HGT) from Wolbachia endosymbiotic bacteria to their eukaryotic hosts is a topic of considerable interest and debate.Recent transfers of genome fragments from Wolbachia into insect BCAA SPLASH WATERMELON chromosomes have been reported, but it has been argued that these frag

BackgroundUniversal newborn screening changed the way medical providers think about the presentation of cystic fibrosis (CF).Before implementation of universal screening, it was common for children with CF to present with failure to thrive, nutritional deficiencies, and recurrent infections.Now, nearly all cases of CF are diagnosed by newborn scree

Malignant melanoma originates from melanoma cells, which derive from the neuroectoderm of the ectodermal mucosa.The chameleonic Guards presentation of malignant melanoma, its often asymptomatic nature, the rarity of the lesion, the grim prognosis, and the imperative for highly specialized treatment are critical factors that merit careful considerat